Biologists see combined structure of cold virus and receptor molecule

Biologists determined the combined structure of a common-cold virus attached to a molecule that enables the virus to infect its host, information that ultimately may help researchers develop methods for treating certain viral infections.

'Frozen pictures' allow far-reaching glimpse into the cell’s protein factory

The structure of the small ribosomal subunit has been determinded at the highest resolution ever achieved by a team of Weizmann Institute and Max Planck Society scientists.

Key progress by Weizmann scientists in the race to unravel ribosomal structure

A team of Weizmann Institute and Max-Planck Society scientists has determined the structure of the small ribosomal subunit at the highest resolution ever achieved, including the site where protein biosynthesis begins.

New insights into protein synthesis and Hepatitis C infections

Scientists have uncovered key new information towards understanding the crucial first step in protein synthesis, the process by which the genetic code, harbored within DNA and copied into RNA, is translated into the production of proteins.

In Vitro Evaluation of Frozen-Thawed Stallion Semen: A Review

The article reviews methods used for in vitro evaluation of sperm, with particular emphasis on frozen-thawed stallion sperm.

The use of a new miniature cryoprobe for ablation of bone tissue: In vivo assessment of the probe and application of the method to bone in a sheep model

In this study, cryoablation methodology was applied to bone and the cooling capacity of the probe was examined in vitro and in vivo.

Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus

Endoscopic cryo spray ablation warrants further investigation as a palliative treatment modality for esophageal cancer. This is the first reported case in the medical literature.

Technique shows ratcheting motion of ribosomes

Using a technique called three-dimensional cryo-electron microscopy, researchers have detected a ratcheting rotation deep inside the cell's tiny protein-making "factory" at a key point in the protein construction process.

Zooming in on the protein-conducting channel

Researchers have gained the most detailed view yet of the heart of the translocon, a channel through which newly constructed proteins are inserted into the cell membrane.

UT Southwestern to get powerful electron microscope

To focus at the molecular-level on the mechanics of human cells with a clarity rarely possible, UT Southwestern Medical Center at Dallas installed a $1.6 million state-of-the-art electron microscope and related equipment

Hepatitis C virus clamps onto protein synthesis machinery

The scientists probed how HCV utilizes its IRES by using cryo-electron microscopy to create high-resolution three-dimensional maps of the viral IRES RNA bound to a ribosome subunit, called the 40S subunit

US woman gives birth to baby from world's first frozen donor egg bank

Cryo eggs international is world's first frozen egg bank

Capturing cell protein production in action could help fight antibiotic resistance

The fight against antibiotic resistance could be aided by new 3D images of the final steps involved in manufacturing proteins in living cells

DNA integrity and motility of human spermatozoa after standard slow freezing versus cryoprotectant-free vitrification

The aim of our study was to compare slowly frozen and vitrified spermatozoa in terms of their post-thaw DNA integrity and motility.

Patented Process Preserves Transplant Tissues/Organs

A patent was issued recently to Organ Recovery Systems of Chicago for a method to chill body tissues and organs well below freezing without forming ice crystals.

Jefferson Surgeons Using New Technique To "Melt" Tumors

Surgeons at Thomas Jefferson University Hospital are using a new technique to essentially "melt" away cancerous liver tumors.

First multi-center trial shows cryosurgery successful at treating some early-stage breast cancer

Imagine being treated for breast cancer right in your doctor's office, with an incision as small as a pinprick to show for it.

Cryosurgery Offers New Hope For Liver Cancer Patients

A surgical procedure that literally freezes cancer in its tracks is giving hope to patients who have not been helped by traditional therapy.

The making and breaking of microtubules

Cryo-electron microscopy (cryo-EM) is capable of capturing such polymer structures without having to break them down and crystallize single subunits for x-ray diffraction analysis.

Unraveling the viral mechanism

Using powerful computer tools and cryo-electron microscopes, researchers at Baylor College of Medicine unmasked the secrets of a tiny virus that infects bacteria...