Hepatic Stem Cells: In Search of

In this review, the authors discuss the different definitions and functions of hepatic progenitor cells as well as the current research efforts examining their therapeutic potential.

Concise Review: Telomere Biology in Normal and Leukemic Hematopoietic Stem Cells

The identification of the leukemic stem cell, along with the desire to target this population with anti-leukemia therapy, demands that telomerase biology be fully understood in this cell compartment.

The cell cycle DB: a systems biology approach to cell cycle analysis

The aim of resource is to give an exhaustive view of the cell cycle process

Functional Sieve Element Protoplasts

SE protoplasts promise to be a powerful tool in studying the membrane biology of SEs with inherent implications for the understanding of long-distance transport and signaling

An efficient rapid system for profiling the cellular activities of molecular libraries

This methodology provides a powerful tool for unraveling the cellular biology and molecular pharmacology of both naturally occurring and synthetic chemical diversity.

Metal-Responsive Transcription Factors That Regulate Iron, Zinc, and Copper Homeostasis in Eukaryotic Cells

This review focuses on the role that metal-responsive transcription factors have in regulating trace metal metabolism.

Autophagy in the Eukaryotic Cell

This review focuses on the yeast S. cerevisiae because of the recent advances in understanding of the molecular mechanism of autophagy, pexophagy, and Cvt transport in this organism.

DNA and the chromosome – varied targets for chemotherapy

In this review, the authors discussed some of the new drugs aimed at primary DNA sequences, DNA secondary structures, and associated proteins.

TBLR1 regulates the expression of nuclear hormone receptor co-repressors

In this paper, the authors report the structure of the TBLR1 gene and analyze its pattern of expression.

Reversing cancer cells to normal cells

Tumor cells exposed to embryonic microenvironment of stem cells

Cancer cells 'reprogram' energy needs to grow and spread, study suggests

Studying a rare inherited syndrome, researchers have found that cancer cells can reprogram themselves to turn down their own energy-making machinery and use less oxygen

'Nurse cells' make life and death decisions for infection-fighting cells

"Nurse cells" play an important role in deciding which developing infection-fighting cells, called T cells, live and which die, according to research

A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells

Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells

UCLA researchers reprogram normal tissue cells into embryonic stem cells

New technique could allow for cell reprogramming without use of controversial cloning methods

Cancer stem cells can go it alone

At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them.

Deakin University research finds rogue cells that could cause spread of breast cancer

Stephanie Lebret completed the study for her PhD at Deakin's Centre for Cellular and Molecular Biology under the supervision of Associate Professor Leigh Ackland.

Findings Offer Clue To How Molecule Can Both Stimulate, Suppress Cell Growth

Scientists are puzzled by the fact that the molecule known as transforming growth factor-beta (TGF-b) generally stops cells from multiplying but at other times promotes cell growth.

Extragenic suppression analysis of TS mutants using Sec61

During synthesis, secretory and membrane proteins are cotranslationally translocated into the lumen of the endoplasmic reticulum through an aqueous gated channel. Proper folding, degradation, and transport of many polypeptides depend on a diverse set of

New Research Identifies Human Enzyme That Could Be Programmed To Kill Cancer Cells

A new study conducted by scientists at Children's Hospital Oakland Research Institute (CHORI) identifies a specific enzyme that can cause the death of cancer cells.

One signal elicits thousands of answers

Cell signaling mechanisms often transmit information via protein modifications, most importantly the reversible attachment of phosphate, the so-called protein phosphorylation.