Recombinant expression of human cathelicidin (hCAP18/LL-37) in Pichia pastoris

The constitutive expression of human cathelicidin LL-37 antimicrobial peptide was achieved using the methylotrophic yeast, Pichia pastoris.

Negative selection of chronic lymphocytic leukaemia cells using a bifunctional rosette-based antibody cocktail

High purity of tumour samples is a necessity for accurate genetic and expression analysis and is usually achieved by positive selection in chronic lymphocytic leukaemia (CLL).

Detection of aromatic catabolic gene expression in heterogeneous organic matter used for reduction of volatile organic compounds (VOC) by biofiltration

A qualitative procedure of purified DNA/RNA co-extraction from complex organic matter, used as biofilter support for removing volatile organic compounds, was set up and applied to detect xylene monooxygenase gene expression by RT-PCR.

Scientists 'paint' viruses to track their fate in the body

Biologists from Austria and Singapore developed a technique that adds a new twist on the relationship between biology and art.

Researchers find quick way to make human monoclonal antibodies against flu

Human monoclonal antibodies (mAbs)--highly specific, identical, infection-fighting proteins produced in large quantities in the lab in cell lines that are derived from a single cell--against influenza can be rapidly produced in the lab

Invention gives improved gene technology analysis

A patent for a system that gives more reliable results in gene technology-based diagnostic tests has been granted to researchers at the Norwegian Institute of Public Health (NIPH).

Researchers pilot new electronic system for infectious illness

Researchers have created and tested a set of computer programs that use electronic medical records to help clinicians detect contagious illness and automatically report them to public health departments.

Scientists develop strategy to rapidly describe outbreak strains with next-generation DNA sequencing

In the event of an outbreak or a bioterrorist attack, rapid identification of the genetic changes responsible for virulence or drug resistance is essential to mounting an effective response.

Promising new nanotechnology for spinal cord injury

A spinal cord injury often leads to permanent paralysis and loss of sensation below the site of the injury because the damaged nerve fibers can't regenerate.

U of M researchers create beating heart in laboratory

University of Minnesota researchers have created a beating heart in the laboratory.

Class of antibiotics can enhance gene-silencing tool

A way to turn off one gene at a time has earned acceptance in biology laboratories over the last decade.

New role for gene that counteracts formation of tumors

Ghent - Scientists from the Flanders Interuniversity Institute for Biotechnology (VIB) have achieved a new breakthrough in cancer research.

System to analyze beating heart stem cells could lead to heart attack treatments

New research at the University of Nottingham, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), is paving the way for techniques that use stem cells to repair the damage caused by heart attacks.

New target for anti-flu drug development

A new mechanism by which flu virus may kill the cell, and how this could be used to fight the virus

Human derived stem cells can repair rat hearts damaged by heart attack

When human heart muscle cells derived from embryonic stem cells are implanted into a rat after a heart attack, they can help rebuild the animal's heart muscle and improve function of the organ...

New system to lead to safer drugs for tropical disease leishmaniasis

The fight against the deadly tropical disease Leishmaniasis, also known as black fever, has been boosted by scientists at the University of Durham, whose new screening system has raised the possibility of new, safer drugs.

New class of drug offers hope to treatment-resistant AIDS patients

Major license to Georgia biopharmaceutical company benefits UGA

Impact of Lactic Acid Bacteria on Dendritic Cells from Allergic Patients in an Experimental Model of Intestinal Epithelium

Lactic acid bacteria are Gram positive nonpathogenic commensal organisms present in human gastrointestinal tract.

Expression by Streptomyces lividans of the Rat Alpha Integrin CD11b A-Domain as a Secreted and Soluble Recombinant Protein

The authors herein report the expression and secretion of the rat CD11b A-domain using the same LSSP and S. lividans as host strain.

The Many Facets of SDF-1alpha CXCR4 Agonists and Antagonists on Hematopoietic Progenitor Cells

Stromal cell-derived factor-1alpha (SDF-1alpha) has pleiotropic effects on hematopoietic progenitor cells (HPCs).