Streptomycin production by Streptomyces griseus can be modulated by a mechanism not associated with change in the adpA component of the A-factor cascade
S. griseus carries a single close homologue of atrA and that expression of S. coelicolor AtrA in S. griseus causes a DNA binding-dependent reduction in streptomycin production...
Fatty acids reduce the tensile strength of fungal hyphae during cephalosporin C production in Acremonium chrysogenum
Fragmentation rate constants were used to elucidate relationships between morphological changes and addition of fatty acids during cephalosporin C production in Acremonium chrysogenum M35
Is the treatment of Parkinson's disease possible with a new neurotrophic factor in the future?
Parkinson’s disease is a degenerative brain disease characterized by the loss of dopamine neurons in the midbrain-area called Substantia Nigra.
Progenika Biopharma presents a biochip that guarantees safety in blood transfusions
The Basque biotechnology company, Progenika Biopharma, devoted to research and development in personalised medicine, have presented a DNA biochip, known as BLOODchip
New chimeric mouse model for human liver diseases, drug testing
Cells cultured in the lab are like a fish out of water.
MIT: Remote-control nanoparticles deliver drugs directly into tumors
MIT scientists have devised remotely controlled nanoparticles that, when pulsed with an electromagnetic field, release drugs to attack tumors.
MIT: 'Micro' livers could aid drug screening
MIT researchers have devised a novel way to create tiny colonies of living human liver cells that model the full-sized organ.
Biotechnology and the Pharmaceutical Industry New Cardiovascular Drugs
This review will concentrate on drugs produced by genetic engineering processes.
Addressing the Unmet Medical Need for Safe and Effective Weight Loss Therapies
A minireview of the current status of potential weight loss approaches that are in development by the pharmaceutical and biotechnology industry are discussed.
£2 Million of Yeast Could Triple Available Drug Treatments
Researchers are to employ the humble yeast cell to greatly increase – perhaps even triple - the number of drug treatments for common diseases such as allergies, asthma, obesity, type 2 diabetes, schizophrenia, heart disease, osteoporosis and cancer.
Two More Potential HIV Vaccines
Despite long-term researchers' efforts, efficient human immunodeficienct virus (HIV) vaccine has not been created yet.
Sydney scientists discover and license breakthrough anti-inflammatory treatment
Scientists from the Garvan Institute of Medical Research have developed what could be the next big blockbuster treatment for inflammatory diseases such as rheumatoid arthritis and asthma.
Early Promise Of Simple Screening For Coeliac Disease (p 945)
The new approach is likely to be more user-friendly for patients as it is less invasive than conventional screening which relies on biopsy.
Dartmouth and GlycoFi report full humanization of therapeutic proteins from yeast
Research advances drug development efforts
Malaria Vaccine Initiative And Apovia Inc. Partner To Pursue Rapid Development Of Novel Malaria Vaccine
Because of the way the malaria parasite develops within its victims, many scientists believe that the most effective vaccine will ultimately have to target more than one stage of its development cycle.
TANGO - towards faster prognosis of Alzheimer's and Parkinson's diseases?
A large number of diseases - including Alzheimer's disease, Parkinson's disease, and mad cow disease - are the result of proteins that erroneously assume the wrong shape, causing them to stick to each other.
Dartmouth, GlycoFi researchers make leap in protein bioengineering
Investigators at Dartmouth's Thayer School of Engineering, the Dartmouth-Hitchcock Medical Center, and the biotechnology firm GlycoFi, Inc., report a breakthrough in using yeast to produce antibodies with human sugar structures.
UCSB researchers discover new biotechnology to identify
This technology should help solve the puzzles of cancer, Alzheimer's, atherosclerosis and infectious diseases.
UCLA Researchers Discover New Method To Generate Human Bone
By studying diseases in which the human body generates too much bone, UCLA researchers have discovered and isolated a natural molecule that can be used to heal fractures and generate new bone growth in patients who lack it.
Protein clue to tailor-made antibiotics
Scientists at the University of York have made a huge leap forward in the search for 'smarter' antibiotics.