Biochemistry

A collection of articles in Biochemistry, the study of the structure and function of cellular components, such as proteins, carbohydrates, lipids, nucleic acids, and other biomolecules, and of their functions and transformations during life processes

Biochemistry Articles

Articular Cartilage Collagen: an irreplaceable framework?

17 Jan 2007

Rating: not rated

New evidence that collagen type III becomes covalently added to the polymeric fabric of adult human articular cartilage is presented.

The Structure and Function of Cartilage Proteoglycans

17 Jan 2007

Rating: 4.76

Cartilage contains a variety of proteoglycans that are essential for its normal function.

Researchers discover new tumor defense system

17 Jan 2007

Rating: not rated

Researchers have discovered that tumors release fatty acids that interfere with the cells that are trying to kill them.

Baby's genes affect mom's cholesterol levels

17 Jan 2007

Rating: 2.33

A group of Belgian researchers has determined that a pregnant woman's ability to metabolize fats is determined not only by her genes but by her baby's genes as well.

Stomach receptor for H. pylori discovered

17 Jan 2007

Rating: 2.20

Scientists have determined that decay-accelerating factor (DAF), a protein found in epithelial cells in the stomach, acts as a receptor for the bacteria Helicobacter pylori.

Disabling A Carb Trigger Reduces Obesity And Appetite

17 Jan 2007

Rating: 7.00

Until about 15 years ago, insulin was believed primarily responsible for turning carbohydrates into fat.

New Polysaccharide May Help Combat Multidrug Resistance In Cancer

17 Jan 2007

Rating: 7.00

Scientists report that a molecule previously thought to play a purely structural and inert role in cells is actually involved in multidrug resistance in cancer.

Beyond The Bonds That Bind: Researchers Discover Hydrogen Can Form Multicenter Bonds

12 Dec 2006

Rating: not rated

Researchers have shown that, under the right circumstances, hydrogen can form multicenter bonds, where one hydrogen atom simultaneously bonds to as many as four or six other atoms.

Hormone Replacement Therapy Reduces Bad Cholesterol, Lp (a)

16 Jan 2007

Rating: 5.29

Hormone replacement therapy may help reduce a woman's risk of heart attack, by lowering blood levels of the most potentially destructive form of cholesterol, according to a study.

Marijuana-like compounds suppress the immune response

16 Jan 2007

Rating: 3.00

A group of Japanese scientists has discovered that cannabinoids can cause some white blood cells to lose their ability to migrate to the sites of infection and inflammation.

The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells

27 Sep 2006

Rating: 4.80

A review on the recent advances in the understanding of the role of the p38 MAPK signaling cascade in CD4 T cells and the consequences that its inhibition provokes in T cell functions in vitro and in vivo.

Summary: Systemic Effects of Inhaled Nitric Oxide

27 Sep 2006

Rating: 1.00

In this article, many of the whole-animal studies regarding the systemic effects of inhaled NO are reviewed in the context of this emerging understanding of the complexities of NO biochemistry.

Coenzyme Q Shortens Life Span Of Worms Substantially, UCLA Chemists Report

26 Sep 2006

Rating: 3.00

A popular dietary supplement, Coenzyme Q, accelerates aging and death in a microscopic worm studied by UCLA biochemists.

UC Riverside Biochemists Develop Technology To Increase Vitamin C In Plants

26 Sep 2006

Rating: 7.75

Biochemist have developed technology that increases the amount of vitamin C in plants, including grains, by increasing the amount of the enzyme that is responsible for recycling vitamin C.

Striking The Right Balance Between Excitation And Inhibition

26 Sep 2006

Rating: not rated

Neurons in the brain and spinal cord come in two flavors, excitatory neurons that transmit and amplify signals, and inhibitory neurons that inhibit and refine those signals

Nuclear Receptor Minireview Series

15 Sep 2006

Rating: 3.67

The nuclear receptor superfamily describes a related but diverse array of transcription factors, which include nuclear hormone receptors (NHRs)1 and orphan nuclear receptors.

Signaling the Unfolded Protein Response from the Endoplasmic Reticulum

15 Sep 2006

Rating: 3.38

The authors discussed the basic components of the UPR pathways, the physiological roles of the UPR signaling, and the future direction of the field.

Ketone Bodies Stimulate Chaperone-mediated Autophagy

15 Sep 2006

Rating: not rated

Study shows that treatment of cells with ketone bodies increased the proteolysis of long-lived proteins under conditions in which most proteolysis is due to Chaperone-mediated autophagy.

A New Class of Peroxisome Proliferator-activated Receptor Agonists with a Novel Binding Epitope Shows Antidiabetic Effects*

17 Aug 2006

Rating: not rated

In here the authors described a new class of PPAR agonists, the 5-substituted 2-benzoylaminobenzoic acids (2-BABAs)...

The channel architecture of aquaporin 0 at a 2.2-Å resolution

17 Aug 2006

Rating: not rated

In this study the x-ray structure of bovine aquaporin 0 (AQP0) was determined to a resolution of 2.2 Å.