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(Science: biology, genetics) A single diploid cell resulting from the fusion of male and female gametes at fertilization (sperm and ovum). The cell resulting from the union of an ovum and a spermatozoon (including the organism that develops from that cell).The fusion of two haploid gametes with the consequential creation of a diploid zygote cell, which can raplidy multiply after this fertilisation of fusion of genetic material occurs.