Stuck on a problem? Get great tutoring at an affordable price with Chegg. Click here to join and get your 1st 30 minutes Free!

Wobble hypothesis

From Biology-Online Dictionary
Jump to: navigation, search

wobble hypothesis

(Science: molecular biology) explains why the base inosine is included in position 1 in the anticodons of various t rNAs, why many mRNA codon words translate to a single amino acid, why there are appreciably fewer t RNAs than mRNA codon types and why the redundant nature of the genetic code translates into a precise set of 20 amino acids.

inosine in position 1 in the anticodon can base pair with A, u or C in position 3 in the mRNA codon, so that for example UCU, UCC, UCA all code for serine using an inosine anticodon.