Difference between revisions of "Nonsuppressible insulin-like activity"

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nonsuppressible insulin-like activity
#redirect [[Insulin-like growth factor 1]]
A [[blood]] [[protein]] ([[nsila]]) which [[mimics]] the [[biological]] [[activity]] of [[insulin]] in [[serum]], but is not suppressed by insulin [[antibodies]]. During [[acid]]-[[ethanol]] [[extraction]] of cohn [[fraction]] III, 10% of the activity is found in the [[supernatant]] (nsila-s) and the remaining activity in the [[precipitate]] (nsila-p). The latter is a [[large]] [[molecular]] [[compound]], much less [[stable]] than the [[soluble]] fraction. Nsila-s is a more [[potent]] [[growth factor]] than insulin and [[exhibits]] [[sulfation]] activity.

Latest revision as of 00:20, 20 October 2019