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Inflammatory cell

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noun, plural: inflammatory cells

Any of the cellular component of inflammation


Inflammation is a part of the tissue repair process. It may also occur as a physiological response to the presence of pathogens, chemical irritants, and damaged cells in the body. Cellular elements that are at work are the white blood cells (leukocytes).

At the onset of inflammation, the first to respond are the neutrophils. Neutrophils are granulocytes that are active in the phagocytosis of microorganisms.

Apart from neutrophils, macrophages and monocytes are also capable of phagocytosis. They are also capable of phagocytosis. These cells dominate especially when inflammation becomes chronic.

Mast cells are cells residing in tissues. They are known for their role in allergic and anaphylactic responses. They also play a key role in the inflammatory process. Histamine, which is a major granule found inside the mast cell, is released into the interstitium when the mast cell is activated through chemical mediators, or damaged through direct injury. Histamine causes local arteriolar vasodilation and increased local capillary permeability. As a result, the injured tissue swells from the arrival of morewhite blood cells, plasma proteins, and phagocytes to the site.

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