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From Biology-Online Dictionary | Biology-Online Dictionary
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1. A shoe for horses, consisting of a narrow plate of iron in form somewhat like the letter u, nailed to a horses hoof.

2. Anything shaped like a horsehoe crab.

3. (Science: zoology) The limulus of horsehoe crab.

(Science: medicine) Horsehoe head, a bat of the genus Rhinolophus, having a nasal fold of skin shaped like a horsehoe.