(Science: syndrome) supravalvular aortic stenosis, mental retardation, elfin facies, and transient hypercalcaemia in infancy. It affects both sexes, with onset at birth or early infancy. Its aetiology is unknown. The primary disturbance begins in utero. There is a familial tendency but no genetic basis is apparent. It is possibly an abnormality of vitamin d metabolism. Its prognosis depends upon the degree of malformation and surgical correction. Williams' syndrome --> cardiofacial syndrome
Synonym: williams' syndrome.