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White-matter disease

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white-matter disease

(Science: radiology) Demyelinating (myelinoclastic), destruction of existing myelin, acquired diseases with inflammatory characteristics, includes: MS, pML, encephalomyelitis, also may be due to anoxia, infarct, tumour, radiation dysmyelinating, abnormal myelin formation or maintenance, two groups: primary white-matter diseases: leukodystrophies, involve gray matter: Niemann-pick, Gaucher, Tay-Sachs