Vinblastine

From Biology-Online Dictionary
Jump to: navigation, search

vinblastine

(Science: drug, oncology) alkaloid (818D) isolated from Vinca (periwinkle): binds to tubulin heterodimer and induces formation of paracrystals rather than tubules. Net result is that microtubules disappear as they disassemble and are not replaced. Used in tumour chemotherapy.