Uridylic acid

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uridylic acid

uridine esterified by phosphoric acid on one or more sugar hydroxyl groups; uMP is typically uridine 5'-monophosphate; 2' and 3' derivatives also occur; precursor for the biosynthesis of other pyrimidine nucleotides.

Synonym: uMP synthase, uridine 5'-monophosphate.

Uridylic acid synthase, a bifunctional enzyme that contains the activities of both orotate phosphoribosyltransferase and orotidine-5'-monophosphate decarboxylase; catalyses a key step in pyrimidine biosynthesis; a deficiency of this enzyme leads to orotic aciduria.