Triosephosphate isomerase

From Biology-Online Dictionary
Jump to: navigation, search

triosephosphate isomerase

(Science: biochemistry, enzyme) An isomerizing enzyme that during glycolysis, catalyses the reversible interconversion of d-glyceraldehyde 3-phosphate to dihydroxyacetone phosphate and viceversa. A reaction of importance in glycolysis and gluconeogenesis.

A deficiency in humans causes congenital nonspherocytic haemolytic anaemia and severe neurological deficits.

Synonym: phosphotriose isomerase.

chemical name: D-glyceraldehyde-3-phosphate ketol isomerase

registry number: EC