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A foreign antigen that suppresses immune response, or produces immune tolerance.


In comparison with immunogen that induces an immune response, a tolerogen evokes immune tolerance.

Instead of inducing the immune system to be active, the tolerogen binds to the antigen receptor of the lymphocytes in order to suppress it.

Related forms: tolerogenic (adjective)

Variant: tolerogenic antigen

Compare: immunogen
See also: antigen