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Tissue-inhibitor of metalloproteinase-1

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tissue-inhibitor of metalloproteinase-1

(Science: chemical) A member of the family of tissue inhibitor of metalloproteinases. It is a n-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumour invasion in vitro.

Pharmacological action: antineoplastic agent, protease inhibitors.