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alpha-(4,5,6,7-tetrahydroisoxazolo[5,4-c] pyridin-3-ol;an agonist at gamma-aminobutyric acid (gABA) type A receptors. Unlike other agonists of this type, upon systemic administration tHIP penetrates the blood-brain barrier and is used as a pharmacological tool to explore gABA receptor function in the brain and spinal cord.