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Terminal addition enzyme

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terminal addition enzyme --> DNA nucleotidylexotransferase

(Science: enzyme) A non-template-directed dNA polymerase normally found in vertebrate thymus and bone marrow. It catalyses the elongation of oligo- or polydeoxynucleotide chains and is widely used as a tool in the differential diagnosis of acute leukaemias in man.

Chemical name: Nucleoside-triphosphate:DNA deoxynucleotidylexotransferase

Registry number: EC 2.7.7.31