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Sterigmatocystin

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sterigmatocystin

(Science: chemical) 3a,12c-dihydro-8-hydroxy-6-methoxy-7h-furo(3',2':4,5)furo (2,3-c)xanthen-7-one. A carcinogenic mycotoxin produced in high yields by strains of the common molds, aspergillus versicolor, a. Nidulans, and an unidentified species of bipolaris. It causes necrosis of the liver and kidney and has an inhibitory effect on orotic acid incorporation into nuclear RNA.

Pharmacological action: carcinogens.

Chemical name: 7H-Furo(3',2':4,5)furo(2,3-c)xanthen-7-one, 3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR-cis)-