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Staurosporine

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staurosporine

(Science: chemical) A potent protein kinase c inhibitor that enhances camp-mediated responses in human neuroblastoma cells. (biochem biophys res commun 1995;214(3):1114-20)

Pharmacological action: carcinogens, enzyme inhibitors, radiation-sensitizing agents.

Chemical name: 8,12-epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(_)-