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1. Destitute of spirit; wanting animation; wanting cheerfulness; dejected; depressed.

2. Destitute of vigor; wanting life, courage, or fire. A men so faint, so spiritless, So dull, so dead in lock, so woebegone. (Shak)

3. Having no breath; extinct; dead. The spiritless body. Spiritlessly, Spiritlessness.