Simmonds disease

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Simmonds' disease

anterior pituitary insufficiency due to trauma, vascular lesions, or tumours; usually developing postpartum as a result of pituitary necrosis caused by ischemia during a hypotensive episode during delivery; characterised clinically by asthenia, loss of weight and body hair, arterial hypotension, and manifestations of thyroid, adrenal, and gonadal hypofunction.

Synonym: hypophysial cachexia, pituitary cachexia.