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From Biology-Online Dictionary | Biology-Online Dictionary
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To make sharp. Specifically:

To give a keen edge or fine point to; to make sharper; as, to sharpen an ax, or the teeth of a saw.

To render more quick or acute in perception; to make more ready or ingenious. The air . . . Sharpened his visual ray To objects distant far. (milton) He that wrestles with us strengthens our nerves and sharpens our skill. (Burke)

To make more eager; as, to sharpen men's desires. Epicurean cooks Sharpen with cloyless sauce his appetite. (Shak)

To make more pungent and intense; as, to sharpen a pain or disease.

To make biting, sarcastic, or severe. Sharpen each word. .

To render more shrill or piercing. Inclosures not only preserve sound, but increase and sharpen it. (bacon)

To make more tart or acid; to make sour; as, the rays of the sun sharpen vinegar.

To raise, as a sound, by means of a sharp; to apply a sharp to.

Origin: See Sharp.