Confused and have questions? We’ve got answers. With Chegg Study, you can get step-by-step solutions to your questions from an expert in the field. If you rather get 1:1 study help, try 30 minutes of free online tutoring with Chegg Tutors.

Serglycin

From Biology-Online Dictionary | Biology-Online Dictionary
Jump to: navigation, search

serglycin

(Science: protein) An intracellular proteoglycan, found particularly in the storage granules of connective tissue mast cells. The core protein consists of 153 amino acids with 24 serine glycine repeats between amino acids 89 and 137, hence the name.

The serine glycine repeats are the linkage sites for _15 glycosaminoglycan chains that are either heparin or highly sulphated chondroitin sulphate. These negatively charged chains are thought to concentrate positively charged proteases, histamine and other molecules within the storage granules.