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Salmonella typhimurium

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Definition

A gram-negative pathogenic bacterium associated in gastroenteritis in humans and other mammals.

Noun

Supplement

Salmonella typhimurium has a lipopolysaccharide at the outer membrane composed of phosphorylated glucosamines which attached to fatty acids that protect the bacteria from the harsh environment. It has the ability to endure acetylation of O-antigen responsible for host immune response that changes its conformation and makes it hard for antibodies to distinguish.

Salmonella typhimurium is able to produce autoinducers, a small signaling molecule that increases the concentration of glucose and recycled by the bacterial cell which permits cells to determine the metabolic potential of the environment. It cause scuttle of white blood cell into the mucosa and throws off between absorption and secretion leading to diarrhea.

Salmonella typhimurium infects through direct contact with nonphagocytic cells that induces the arrangement of appendages on the bacterial surface in which its appendages is shorter than flagella causing the host cytoskeleton to rearrange and permits the bacteria to enter the cell. When it enter the epithelial lining in the intestine makes cell ruffling that temporarily damage the microvilli on the surface of the cell.

Scientific classification:

Kingdom: Bacteria

Phylum: Proteobacteria

Class: Gammaproteobacteria

Order: Enterobacteriales

Family: Enterobacteriaceae

Genus: Salmonella

Species: Salmonella typhimurium

See also:

• Bacteria

• Gastroenteritis