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(Science: chemical) A macrolide antibiotic of the oligomycin group, obtained from streptomyces rutgersensis. It is used in cytochemistry as a tool to inhibit various atpases and to uncouple oxidative phosphorylation from electron transport and also clinically as an antifungal agent.

Pharmacological action: antibiotics, antifungal, antibiotics, macrolide, enzyme inhibitors, uncoupling agents.

Chemical name: Oligomycin A, 26-demethyl-