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From Biology-Online Dictionary
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1. Having a bay, chestnut, brown, or black colour, with gray or white thickly interspersed; said of a horse. Give my roan a drench. (Shak)

2. Made of the leather called roan; as, roan binding.

(Science: zoology) Roan antelope, a very large south african antelope (Hippotragus equinus). It has long sharp horns and a stiff bright brown mane. Called also mahnya, equine antelope, and bastard gemsbok.

Origin: F. Rouan; cf. Sp. Roano, ruano, It. Rovano, roano.

1. The colour of a roan horse; a roan colour.

2. A roan horse.

3. A kind of leather used for slippers, bookbinding, etc, made from sheepskin, tanned with sumac and coloured to imitate ungrained morocco. Roan tree.

(Science: botany) See rowan tree.