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Rhesus disease

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Definition

noun

A type of hemolytic disease of the fetus or newborn which involves the incompatibility of the Rhesus blood group of the mother and her offspring.


Supplement

For example, the mother is rH- while the fetus is rH+. It results in the immune system of the rH- mother to produce antibodies that enter fetal circulation and attack the red blood cells of the rH+ fetus, resulting in the hemolysis and anemia in fetus. Symptoms include jaundice, anemia, enlarged liver and spleen.


Abbreviation: Rh disease
Variant:

  • RhD Hemolytic Disease of the Newborn
  • Rhesus D Hemolytic Disease of the Newborn or RhD HDN

See also: erythroblastosis fetalis, Rhesus blood group