Rh disease

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A type of hemolytic disease of the fetus or newborn which involves the incompatibility of the Rhesus blood group of the mother and her offspring.


For example, the mother is rH- while the fetus is rH+. It results in the immune system of the rH- mother to produce antibodies that enter fetal circulation and attack the red blood cells of the rH+ fetus, resulting in the hemolysis and anemia in fetus. Symptoms include jaundice, anemia, enlarged liver and spleen.


  • Rhesus disease
  • RhD Hemolytic Disease of the Newborn
  • Rhesus D Hemolytic Disease of the Newborn or RhD HDN

See also: erythroblastosis fetalis, Rhesus blood group