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Reticular fibre

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reticular fibre

(Science: cell biology) A fine fibre of reticulin found in the extracellular matrix.

They are fibres of type III collagen which form the distinctive loose connective tissue stroma of embryonic tissues, mesenchyme, red pulp of the spleen, cortex and medulla of lymph nodes, and the haematopoietic compartments of bone marrow and comprise a substantial portion of the collagen fibres of the skin, blood vessels, synovial membrane, uterine tissue, and granulation tissue.

They are characterised by their organization as a reticular meshwork of fine filaments and an affinity for silver and for periodic acid-Schiff stains.