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Quisqualic acid

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quisqualic acid

(Science: chemical) alpha-amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid. An agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of quisqualis chinensis.

Pharmacological action: excitatory amino acid agonists.

Chemical name: 1,2,4-Oxadiazolidine-2-propanoic acid, alpha-amino-3,5-dioxo-, (S)-