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Oriental cholangio-hepatitis

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Definition

noun

A condition characterized by cholangitis with hepatolithiasis


Supplement

Oriental cholangiohepatitis is a condition characterized by intra- and extrahepatic bile duct strictures and dilations filled with soft pigmented stones. It is prevalent in Asia, particularly in Hong Kong, China, Taiwan, Korea, Japan, Indonesia, and the Philippines.1

The condition is associated with recurring cholangitis, i.e. bacterial infection of the bile duct due to the bile duct being partially obstructed by gallstones. There is also a strong association with Clonorchis sinensis (liver fluke) or Ascaris lumbricoides hepatobiliary infestations. The presence of gallstones in biliary ducts of the liver is referred to as hepatolithiasis. The common symptoms include fever, jaundice, leukocytosis, and recurrent RUQ pain. Possible complications may be liver abscess, septicemic sock, or cholangiocarcinoma. This condition was once the most common cause of emergency abdominal surgery during the 1960s.


Synonym(s):

  • Recurrent pyogenic cholangitis
  • cholangiohepatitis
  • Hong Kong disease
  • oriental cholangitis
  • oriental cholangiohepatitis
  • biliary obstruction syndrome of the Chinese
  • oriental cholangitis

See also:


Reference(s):
1 Tsui, W., Chan, Y., Wong, C., Lo, Y., Yeung, Y., and Lee, Y. (2011). "Hepatolithiasis and the Syndrome of Recurrent Pyogenic Cholangitis: Clinical, Radiologic, and Pathologic Features". Seminars in Liver Disease. 31 (01): 033–048.