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Protoveratrine a and b

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protoveratrine A and B

A mixture of two alkaloids isolated from veratrum album; they exert their main effect upon the cardiovascular system through the carotid sinus receptors and vagal sensory endings in the heart; they cause vasodilation and are thought to bring about a redistribution to all vascular beds and thus to induce a fall in blood pressure; used in certain forms of hypertension; the maleates have the same actions.