Proton pump inhibitor

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proton pump inhibitor

(Science: pharmacology) A group of anti-ulcer medications which work by binding to H_/K_ aTPase, an enzyme which is found on the secretory surface of parietal cells. It thereby inhibits the final transport of hydrogen ions (via exchange with potasium) into the gastric lumen.

Examples of proton pump inhibitors include omeprazole and lansoprazole.