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1. That which prognosticates; a sign by which a future event may be known or foretold; an indication; a sign or omen; hence, a foretelling; a prediction. That choice would inevitably be considered by the country as a prognostic of the highest import. (Macaulay)

2. (Science: medicine) A sign or symptom indicating the course and termination of a disease.

Synonym: sign, omen, presage, token, indication.

Origin: L. Prognosticum, Gr., cf. F. Pronostic, prognostic. See Prognostic.