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Procollagen-proline dioxygenase

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procollagen-proline dioxygenase

(Science: enzyme) A mixed-function oxygenase that catalyses the hydroxylation of a prolyl-glycyl-containing-peptide, usually in protocollagen, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilises molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate.

Chemical name: Procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase

Registry number: EC 1.14.11.2