Pravastatin

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pravastatin

(Science: chemical) An antilipaemic fungal metabolite isolated from cultures of nocardia autotrophica. It acts as a competitive inhibitor of hmg coA reductase (hydroxymethylglutaryl CoA reductases).

Pharmacological action: anticholesteraemic agents, hydroxymethylglutaryl-CoA reductase inhibitors.

Chemical name: 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha))-