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Potter sequence

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Definition

noun

A condition characterized by symptoms similar to Potter syndrome, e.g. clubbed feet, pulmonary hypoplasia, cranial anomalies, etc., due to inadequate amniotic fluid surrounding the developing fetus


Supplement

Potter sequence is a condition resembling the Potter syndrome. Potter syndrome is one in which the fetus has an atypical physical appearance as a result of oligohydramnios. Oligohydramnios pertains to the inadequate amount of amniotic fluid within the amniotic sac. The amniotic fluid helps expand the amniotic sac from where the growing fetus is kept afloat. It provides a space for the fetus to move and grow as well as cushion the growing fetus from physical injuries. Oligohydramnios provides little space for the growth of the fetus. It also leads to deformations in the morphogenesis of the fetus. Another complication that may arise, which is life-threatening, is a hypoplastic lung. A hypoplastic lung is an underdeveloped lung and life-threatening. The underdeveloped lung due to oligohyramnios may lead to inefficient lung function, particularly oxygenation, and to perinatal death.1 Potter syndrome is associated with renal agenesis. It is when the kidney did not develop in the first few weeks of gestational age. Without the kidneys, the fetus would not be able to add up to the amniotic fluid. In Potter sequence, this condition is similar to Potter syndrome in terms of the occurrence of oligohydramnios although the fetus has kidneys. It may likely be due to the broken amniotic sac mid-pregnancy or due to dysfunctional kidneys of the fetus.2


Variant(s):

  • Potter's sequence

Also called:

  • Oligohydramnios sequence

See also:


Reference(s):
1 Oligohydramnios. Biology-Online.org Dictionary. Retrieved from [[1]].
2 Henley, A. & Kohner, N. (2003). When A Baby Dies: The Experience of Late Miscarriage, Stillbirth and Neonatal Death. Routledge. p.201.