Stuck on a problem? Get great tutoring at an affordable price with Chegg. Click here to join and get your 1st 30 minutes Free!

Peptidyltransferase

From Biology-Online Dictionary
Jump to: navigation, search

peptidyltransferase

(Science: enzyme) An enzyme that catalyses the transfer of aminoacyl-tRNA to formyl-methionine-tRNA or peptidyl-tRNA during peptide chain elongation. It is a part of the 50 s (bacteria) and 60 s (eukaryotes) ribosomal subunits.

integral enzymic activity of the large subunit of a ribosome, catalysing the formation of a peptide bond between the carboxy terminus of the nascent chain and the amino group of an arriving tRNA associated amino acid.

Chemical name: Peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase

Registry number: EC 2.3.2.12