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noun, plural: pegiviruses

(virology) A genus of viruses in the taxonomic family Flaviviridae, characterized by their enveloped icosahedral structure, positive single-stranded RNA genome (of about 9400 nucleotides), and infect mammals, such as humans, primates, and greater Indian fruit bats


Flaviviridae is a taxonomic family comprised of viruses containing monopartite, linear, single-stranded RNA enveloped with icosahedral, spherical structure (about 40-60 nm in diameter). This family includes four genera: Flavivirus, Hepacivirus, Pegivirus, and Pestivirus.

Pegiviruses belong to the genus Pegivirus. The genus includes the species Pegivirus A and Pegivirus B. Pegivirus A infects primate hosts such as humans, chimpanzees, and certain New World monkey species. This virus infecting human is particularly referred to as human pegivirus (formerly, hepatitis G virus). It was discovered in 1995. It was previously assumed to be associated with non-A, non-B hepatitis until recent epidemiological studies established no associations between the virus and hepatitis. Nevertheless, the virus is associated with Hodgkin's lymphoma. 1 Structurally, the virus has a positive single-stranded RNA genome with about 9400 nucleotides. Pegivirus B is a virus species initially found in Pteropus giganteus (greater Indian fruit bat).

Scientific classification:

  • Family: Flaviviridae
  • Genus: Pegivirus

See also:

1 Xiang, J. (2002).Human Pegivirus (GB Virus C/hepatitis G virus). Retrieved from [[1]].