A gram-negative nonmotile and non-spore forming bacterium involved as a commensal in the upper respiratory tract of various livestock, poultry and domestic pets particularly cats and dogs.
Pasteurella multocida composed of different strains such as serovars 1, 3 and 4 that causes fowl cholera in commercial poultry particularly layer and breeder poultry worldwide. It expresses wide range of virulence factors due to varied surface molecules lipopolysaccharide.
Pasteurella multocida is implicated in birds and mammals diseases including atrophic rhinitis in pigs, fowl cholera and bovine hemorrhagic septicemia. It also caused zoonotic infection in humans which is transmitted from the bites of domesticated pets such as dogs, cats and birds where it normally thrives as part of the microbiota in respiratory tract.
Pasteurella multocida infections manifested with soft tissue inflammation with high counts of neutrophil and leukocyte that form localized cellulitis. It can also spread to infect other body parts such as respiratory tract causing regional lymphadenopathy wherein a more serious cases resulting to bacteremia that caused endocarditis which sometimes cross the blood-brain barrier causing meningitis.
Species: Pasteurella multocida
• Zoonotic infection