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P-glycoprotein

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p-glycoprotein

(Science: cell biology, protein) A family of integral plasma membrane proteins which, when overexpressed, function as adenosine triphosphate-dependent efflux pumps, causing multidrug resistance.

Mammalian p-glycoproteins are encoded by small mdr gene families. There are several isotypes in multiple species.

See: multidrug transporter.