Opal suppressor

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opal suppressor

(Science: molecular biology) A gene that codes for an altered tRNA so that its anticodon can recognise the opal codon and thus allows the continuation of protein synthesis. A suppressor of an opal mutation is a tRNA that is charged with the amino acid corresponding to the original codon or a neutral substitute. Some eukaryote cells normally synthesise opal suppressor tRNAs. The function of these is not clear and they usually do not prevent normal termination of protein synthesis at an opal codon.