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Nordihydroguaiaretic acid

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nordihydroguaiaretic acid

(Science: chemical) A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.

Pharmacological action: antioxidants, cyclooxygenase inhibitors, keratolytic agents, lipoxygenase inhibitors.

Chemical name: 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-