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Nicardipine

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nicardipine

(Science: chemical) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl) methyl 2-(methyl(phenylmethyl)amino)-3,5-pyridinecarboxylic acid ethyl ester. A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agent.

Pharmacological action: anti-asthmatic agents, antihypertensive agents, calcium channel blockers, vasodilator agents.

Chemical name: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester