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(Science: chemical) A potent direct-acting peripheral vasodilator that reduces peripheral resistance and produces a fall in blood pressure. It is given by mouth in the treatment of severe hypertension unresponsive to other therapy. It is also used topically in the treatment of male-pattern baldness.

Pharmacological action: antihypertensive agents, vasodilator agents.

Chemical name: 2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide