Migration-inhibitory factor

From Biology-Online Dictionary | Biology-Online Dictionary

migration-inhibitory factor

(Science: growth factor) A soluble, nondialysable factor that is produced by sensitised lymphocytes following exposure to a specific antigen. It inhibits macrophage migration and causes adherence.

It was originally defined on the basis of inhibition of emigration of mononuclear cells from capillary (haematocrit) tubes, more recently a 13 kD protein with migration inhibitory activity has been isolated.

Acronym: MIF

Synonym: inhibition factor.