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Mannose-6-phosphate

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Mannose-6-phosphate

(Science: biochemistry) mannose derivative formed by phosphorylation in the golgi Complex of certain mannose residues on N glycan chains of lysosomal enzymes.

Believed to function as targetting signal that causes entry of these enzymes to the lysosomes. The receptor (215 kD) is enriched in specialised pre lysosomes.