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Lypressin

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Definition

noun, plural: lypressins

A porcine vasopressin that is characterized by its amino acid sequence: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2


Supplement

Lypressin (or lysine vasopressin) is one of the members of the vertebrate vasopressin family. Vasopressin is a nonapeptide hormone, being comprised of nine amino acids. The other three forms of vasopressins identified in vertebrates are argipressin, phenypressin, and vasotocin. In particular, the lypressin is comprised of the following amino acid sequence: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2.

The lypressin vasopressin (LVP) is similar to the most predominant form of vasopressin, the argipressin (AVP). The difference lies on the amino acid at position 8. While argipressin has arginine, lypressin has lysine (thus, the names). LVP is found in pigs, warthogs, hippos, and certain marsupials. It has the same functions as that of the AVP in most mammals. It is a vasoconstrictor and an anti-diuretic agent.

LVP is also used clinically. It is used to treat vasopressin deficiency in humans. It is used to treat diabetes insipidus in humans. Felypressin is an example of a synthetic analog of lypressin. Its pharmacological roles include haemostatic, renal agent, and vasoconstrictor agent. The chemical name of LVP: vasopressin, 8-L-lysine-.


Synonym(s):

  • lysine vasopressin (LVH)

See also: